Estrodiol gel, a topical clear gel used in hormone replacement therapy to provide effective relief of symptoms that accompany menopause such as hot flashes as well as vaginal itchiness and dryness. The active ingredient estradiol is the main form of oestrogen in the female body during the maturation and maintenance of the reproductive system. During menopause, the ovaries cease to produce the primary form of oestrogen- Oestrodiol. Therefore applying oestrodiol gel topically works to replace this hormone loss and treat the consequent discomfort affecting the quality of daily life. The gel is absorbed into the skin and into the bloodstream to carry out its functions.

Premarin Vaginal Cream is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness